These symptoms include gas, abdominal belly pain, and constipation. Instead, tell your doctor right away. Some people using Creon have had various skin conditions.
Instead, people reported having skin conditions after Creon was released onto the market. Call your doctor right away if you have a severe rash, itching, or hives while using Creon. In some cases, these symptoms could indicate a serious allergic reaction to the drug. Blurred vision has been reported in some people using Creon. Instead, people reported having blurred vision after Creon was released onto the market. Keep in mind that blurry vision could also be a symptom of either high or low blood sugar levels.
And either can happen in people with certain conditions that Creon is used to manage. In addition, having abnormal blood sugar levels is a possible side effect of Creon. Instead, tell your doctor about any vision problems you have with Creon treatment. You doctor can check to see if you have any conditions that could affect your blood sugar level or cause blurry vision. Some people have had myalgia muscle pain and muscle spasms while taking Creon. Instead, some people reported having myalgia and muscle spasms after Creon was released onto the market.
And Creon is used in people with chronic pancreatitis. If you have new or worsening pain, especially abdominal belly or back pain, talk with your doctor. Some may be a better fit for you than others.
They can tell you about other medications that may work well for you. Note : Some of the drugs listed below are used off-label to treat EPI caused by certain conditions. As with all medications, the cost of Creon can vary.
To find current prices for Creon in your area, check out GoodRx. The cost you find on GoodRx. Keep in mind that you may be able to get a day supply of Creon. If approved by your insurance company, getting a day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost.
Before approving coverage for Creon, your insurance company may require you to get prior authorization. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. The insurance company will review the prior authorization request and decide if the drug will be covered. If you need financial support to pay for Creon, or if you need help understanding your insurance coverage, help is available.
AbbVie, the manufacturer of Creon, offers two support programs that you may qualify for depending on your specific condition.
It also offers the myAbbVie Assist program, which provides free medication to people who qualify. Creon may be available through a mail-order pharmacy. Some Medicare plans may help cover the cost of mail-order medications. Generics tend to cost less than brand-name drugs. Creon may also be used off-label for other conditions.
These specific conditions are described below. Pancreatic enzymes are substances that your pancreas makes to help break down fats, proteins, and carbohydrates from your diet. Creon helps people with EPI by replacing the natural digestive enzymes in their small intestine. For this use, Creon can be given to infants, children, and adults of all ages. Cystic fibrosis CF is a genetic condition. CF causes thick, sticky mucus in certain body parts, including the pancreas.
With CF, the thick, sticky mucus clogs the duct passageway between your pancreas and small intestine. This blocks pancreatic enzymes from reaching your small intestine to help digest food. With CF, you can have maldigestion poor digestion and malabsorption poor absorption , leading to issues including:.
In addition, Creon has been found effective in clinical trials for this purpose. One study included people who were ages 12 to 43 years. Some people took Creon 4, lipase units per gram of total fat intake daily for 5 to 6 days. Then they switched to a placebo no active treatment for 5 to 6 additional days.
Other people took the placebo for 5 to 6 days. Then they switched to Creon at the same dosing as the other group for 5 to 6 additional days. During the study, both groups of people ate a high-fat diet. Researchers reported the following results, which were taken from both groups of people in the study:. Each of the conditions listed above cause EPI because they can affect the health of your pancreas.
Chronic pancreatitis is an ongoing condition. With chronic pancreatitis, you have long-lasting inflammation in your pancreas. It happens when pancreatic enzymes damage your pancreas. This constant damage can affect how well the pancreas works. A pancreatectomy is a surgery to remove all or part of your pancreas. After a partial pancreatectomy, you may not have enough pancreatic enzymes to break down your food. So with either of these surgeries, the ability of your pancreas to make enough digestive enzymes is affected.
A clinical trial looked at using Creon for EPI due to either chronic pancreatitis or pancreatectomy. The trial included people who were ages 32 to 75 years.
Everyone received a placebo treatment with no active drug for 5 days. Then they took a pancreatic enzyme replacement for 16 days. After the first phase of the study, some people took Creon for 7 more days, while others took placebo for 7 more days. Both groups of people ate a diet that was very high in fat.
In this study, researchers looked at the coefficient of fat absorption CFA. This value comes from a stool test that measures how much fat your body absorbs from your diet. CFA increases as your body absorbs more fat. In addition to the uses listed above, Creon may also be used off-label for other conditions.
Below are examples of off-label uses for Creon. IBS is a condition that affects the large intestine. Common IBS symptoms include belly pain, bloating or gas, and changes in stools. Typically, IBS treatment focuses first on lifestyle changes, such diet and stress management.
In one European study , 6. The researchers concluded pancreatic enzyme replacement therapy may lessen certain IBS symptoms. Another small study done in looked at how effective pancrelipase was in relieving IBS-D symptoms compared with a placebo treatment with no active drug. Researchers reported that more people preferred pancrelipase than the placebo for long-term use. And people reported that certain IBS-D symptoms were significantly reduced with pancrelipase compared with no treatment.
Note : Creon contains enzymes called pancrelipase. More studies are needed to confirm whether Creon or other pancreatic enzyme replacement therapies can treat IBS.
In some cases, doctors may prescribe Creon off-label to treat acute pancreatitis. With pancreatitis, you have inflammation in your pancreas. Chronic pancreatitis is long-lasting condition. But acute pancreatitis is a short-term condition.
Mild, acute pancreatitis often heals in a few days with rest and minor care measures. More severe cases may need surgery or other treatments. Certain people with moderate to severe acute pancreatitis have EPI. One European study looked at using Creon to help with recovery in people with EPI due to acute pancreatitis. More research is needed to know whether Creon is safe and effective for this purpose. Feeding tubes may also be recommended for people who need extra calories and nutrition to stay healthy.
The tube goes directly into their stomach or small intestine. Feeding tubes may be inserted into your body through your mouth. Or they may be inserted into a port in your belly that connects to your small intestine. Sometimes, feeding tubes can become clogged. And medical providers may use pancreatic enzyme replacement therapies mixed with other solutions to clear the tubes. Creon is a pancreatic enzyme replacement therapy.
One study looked back through hospital records to learn how effective a dose of Creon was in unclogging feeding tubes compared with the standard pancreatic enzyme therapy Viokase. Researchers reported that about half of the tubes involved were successfully cleared with Creon.
The study included children ages 7 to 11 years. Some children took Creon 4, lipase units per grams of total fat intake daily for 5 to 6 days. Then they switched to taking a placebo no active treatment for 5 to 6 additional days. Other children took the placebo for 5 to 6 days. During the study, both groups of children ate a high-fat diet.
Researchers reported the following results, which were taken from both groups of children in the study:. Another study checked the short-term effectiveness of Creon in 18 infants and children with EPI caused by cystic fibrosis. In this study, ages ranged from 4 months to 6 years. Everyone in the study was given their usual pancreatic enzyme replacement therapy for an average of 18 days.
Then they were given a Creon dose of 7, lipase units per kilogram of body weight per day for an average of 12 days. In this study, children had similar stool fat test results with both treatments. Teiresias advises Creon to change his mind about burying Polynices Creon rejects Teiresias' advice, accusing him of having been bribed to say these things.
However, when the truth is revealed about Jocasta, and Oedipus requests to be exiled, it is Creon who grants his wish and takes the throne in his stead. King Creon, who ascended to the throne of Thebes, decreed that Polynices was not to be buried or even mourned, on pain of death by stoning.
Antigone, his sister, defied the order, but was caught. Creon decreed death, this in spite of her betrothal to his son Haemon. Antigone, moved by love for her brother and convinced of the injustice of the command, buried Polyneices secretly. For that she was ordered by Creon to be executed and was immured in a cave, where she hanged herself. Her beloved, Haemon, son of Creon , committed suicide. Oedipus questions Creon about the oracle.
Creon explains that the gods are angry at Thebes because a murderer is making the city ritually unclean, causing a pollution.
The oracle also said that the murderer is the one who killed Laius, Oedipus ' predecessor as king of Thebes. Ismene iz-ME-nee : Antigone's sister; she'd like to help her sister, but she thinks it's too dangerous. Antigone portrays extremely courageous qualities, and definitely fights for what she believes in.
In the case of Antigone she felt loyal to her brother and felt that she should protect his honor and give him the respect that he deserves even if the king did not agree with her. Creon , the name of two figures in Greek legend. Euripides recounted this legend in his tragedy Medea. The second, the brother of Jocasta, was successor to Oedipus as king of Thebes.
Antigone , moved by love for her brother and convinced of the injustice of the command, buried Polyneices secretly. Her beloved, Haemon, son of Creon, committed suicide. The rule passed to his sons Eteocles and Polynices. However, because of a curse from their father, the two brothers did not share the rule peacefully and died as a result, ultimately killing each other in battle for control of the city.
Upon his death, Eteocles was succeeded by his uncle, Creon. When the catastrophes occur, the messenger directly points to the moral that the worst ill afflicting mortals is a lack of judgment We may well wonder what use judgment is given the limitations of human beings and the inescapable will of the gods. Humans must take a humble, reverential attitude toward fate, the gods, and the limits of human intelligence.
Even though Antigone exhibits a blamable pride and a hunger for glory, her transgressions are less serious than those of Creon. Whereas Antigone breaks a law made by a particular ruler in a particular instance, a law that he could have made differently, Creon violates an unwritten law, a cultural custom. And Haemon, Antigone, and Eurydice can learn nothing more, now that they are dead.
The Chorus, like the audience, struggles to find purpose in violence, though it is not clear that there is any purpose to be found. SparkTeach Teacher's Handbook. Themes Motifs Symbols. Summary Antigone, lines —
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